How to Identify and Treat the Allergy to Semen

The allergy to semen, also known as allergy to sperm, or hypersensitivity to seminal plasma, is an allergic reaction that is rare, which arises as a response of the immune system to the proteins in the semen of the man.

This type of allergy is more common in women, but can also happen in men, causing symptoms such as redness, itching and swelling in the region of the skin that was in contact with the fluid.

Although the allergy to semen the male does not cause infertility, can hinder the process of getting pregnant, especially due to the discomfort caused by the problem. This way, when there is suspicion of allergy is advised to consult a doctor to start treatment with anti-histamines, for example, with the goal of easing the symptoms.

The main symptoms

The most common signs and symptoms of this allergy usually appear in the location that was in direct contact with the semen, and include:


  • Redness in the skin or mucosa;
  • Intense feeling of itching or burning;
  • Swelling of the region.

These symptoms usually appear between 10 and 30 minutes after contact with the semen, and may last up to several hours or days. In some women, the allergy can be so severe that arise other signals that affect the entire body, as red spots on the skin, sensation of a ball in the throat, and difficulty breathing.

Although this is more rare, this type of allergy can also happen in man, which may even have an allergy to their own semen. In these cases, it is possible that may arise symptoms similar to the flu, such as fever, runny nose, and fatigue, a few minutes after ejaculation.

How to confirm the diagnosis

To make the correct diagnosis it is advised to consult a gynaecologist, in the case of a woman, or a urologist, in the case of man. The doctor may need to do several tests to confirm the diagnosis, since there are other conditions that cause the same type symptoms, such as thrush or vaginitis, for example.

However, one way to help identify if semen is the cause of the symptoms, is to assess if they continue to spread even when using condoms during intimate contact, because, if there is direct contact with the semen, can be a sign of another problem.


Who has the most risk of having

Although not know the specific cause that leads to the emergence of allergy to the sperm, it is possible that the risk is greater in people who already have some kind of allergy, such as allergic rhinitis or asthma, for example.

In addition, other factors that seem to increase this risk include:

  • Stay long without having sex;
  • Be in menopause;
  • To use the IUD;
  • Having removed the uterus.

In addition, the semen of men who withdrew part or all of the prostate also seems to cause the largest number of allergic reactions.

How is it treated

The first form of treatment recommended to relieve the symptoms of allergy to semen is in the condom use during the relationship, so try to avoid coming in direct contact with the semen, and, thus, the development of allergy.


However, this form of treatment may not work for people who are trying to become pregnant or for men who have allergy to their own semen, and, therefore, the doctor may prescribe the use of anti-allergic. In more severe cases, the allergy may cause difficulty breathing, the doctor can even prescribe an injection of epinephrine, to be used in cases of emergency.

Another form of treatment is to decrease the sensitivity to semen over time. For this, the doctor collects a sample of semen of the partner and thins. After, will placing a small sample inside the woman’s vagina every 20 minutes, until it reaches the concentration of the sperm. In these cases, it is expected that the immune system to stop responding so exaggerated. During this treatment, the doctor may also advise to have intercourse every 48 hours.

How to Identify and Treat the Allergy to Semen 1

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